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Pickups are items which are not gear, runes, or blueprints. Pickups can be collected with the Interact command while the player is close or, in the case of gems, just by walking on top of them.

All main categories of pickups are:

  • Healing pickups that restore the player's health or reduce Malaise.
  • Scrolls to upgrade player stats.
  • Currency pickups, which award varying amounts of cells or gold.
  • Special pickups serving miscellaneous functions.
  • Keys, which let the player unlock doors.

Healing Pickups[edit | edit source]

Food[edit | edit source]

Food regenerates a fixed percentage of health when eaten (or twice as much if the Gastronomy mutation is active). There are 2 different functional types of food, each with 7 different appearances depending on the selected diet, which is altered by game settings. If untouched by the player, it will be chosen as "Carnivore." Both types of food can add Malaise on Nightmare and Hell difficulties if the piece of food is infected. The amount of malaise given depends on if the food is major or minor. Minor food gives 50 points (1 bar) and major food gives 150 points (3 bars) of malaise.

Minor Foods[edit | edit source]

Minor foods restore 15% of the player's maximum health (30% if Gastronomy Mutation Icon.png Gastronomy is active). They're dropped from enemies, wall and floor runes, and can be purchased from food shops with 0-3BSC active(with 4BSC+, food shops will sell a cough syrup istead).

Name Icon Diet Setting
"Le Croissant"
Small medkit

Major Foods[edit | edit source]

Major foods heal 50% of the player's maximum health (100% if Gastronomy Mutation Icon.png Gastronomy is active). They're found in the same ways minor foods are, as well as in lore rooms, but are rarer.

Name Icon Diet Setting
Big ol' radish
Monster's Eye
"La Baguette"
Large medkit

Other Healing Items[edit | edit source]

These healing items are more uncommon than food and can usually only be encountered under certain conditions.

Type Icon Description Sources
Flask Recharge
Healing Potion 1 Icon.png
Restores 1 Health Flask charge.
  • Passages (1-2 BSC)
  • Food Shops
  • Elites (with Tainted Flask Mutation Icon.png Tainted Flask)
Cough Syrup
Cough Syrup.png
Reduces your Malaise infection level by 30%.
  • Food Shops
Small Cough Syrup
Small Cough Syrup.png
Reduces your Malaise infection level by 1%.
  • Elites (with Extended Healing Mutation Icon.png Extended Healing). This item is defunct in v2.1 however.
  • Note that Small Cough Syrup will still reduce infection level by one point, despite its description.

Scrolls[edit | edit source]

Scrolls are items that increase the player's stats.

Name Icon Effect Sources
Scroll of Power
Adds one point to one of the three stats.
  • Scroll Vats
  • Enemy Drops
  • Cursed Chest
  • Challenge Rift Chest
Assassin's Scroll
Str Skill.png
Adds one point to either Brutality or Tactics.
  • Scroll Vats
  • Enemy Drops
Minotaur's Scroll
Str Hp.png
Adds one point to either Brutality or Survival.
  • Scroll Vats
  • Enemy Drops
Guardian's Scroll
Skill Hp.png
Adds one point to either Tactics or Survival.
  • Scroll Vats
  • Enemy Drops
Epic Scrolls of Power
Adds one point to each one of the three stats.
Scroll Fragment
Scroll Fragments.png
After obtaining four fragments, adds one point to one of the three stats.
  • Scroll Fragment Pedestals
  • Enemy Drops
  • Bosses
  • Scroll Fragments can only be found while 3 or more Boss Stem Cells are active.

Currency Pickups[edit | edit source]

Gold centered[edit | edit source]

Gold is the main currency used for making purchases and weapon upgrades throughout runs. All enemies will drop small amounts of gold when killed that appears as tiny, bright pebbles that automatically fly towards the player to be collected.

Gems[edit | edit source]

Gems give a significant amount of gold when collected. Each one awards a different amount of gold depending on type.

Gems in order of value
Name Icon Description Value Sources
Gold Tooth
Golden Tooth Icon.png
A tooth worth 100 GOLD. He was asking for it... 100
Golden Arrow
Golden Arrow Icon.png
A transmuted arrow worth 100 GOLD. When you care enough to shoot the very best. 100
Shiny Rock
Shiny Rock Icon.png
Totally and utterly worthless. You're not gonna pick that thing up, are you? 100
  • Guaranteed drop from one of the Key Dark Tracker Elites in High Peak Castle
  • Timed door reward
  • Wall runes (uncommon)
  • Random drop from enemies
Malachite Icon.png
Quite common, but you shouldn't have any trouble getting 250 GOLD for it. 250
  • Wall runes (common)
  • Timed door reward
  • The Concierge death reward
  • Random drop from enemies
Amethyst Icon.png
This pretty stone will fetch you 500 GOLD! My precccioussss... 500
  • Wall runes (uncommon)
  • The Concierge death reward
  • Timed door reward
  • Random drop from enemies
Blue Sapphire
Blue Sapphire Icon.png
A magnificent stone worth 1000 GOLD! 1000
  • Wall runes (rare)
  • Timed door reward (rare)
Ruby Icon.png
A precious stone of truly exceptional purity that will fetch you the modest sum of 1500 GOLD! 1500
  • Wall rune (very rare)
  • Cursed Chest reward
  • Guard Corpse on 4th run of save in the Prisoner's Quarters (guaranteed drop)
Corrupted Artifact
Corrupted Artefact Icon.png
This is worth 10000 GOLD, but if you pick it up, you'll be cursed. (20 enemies curse) 10000
  • Random drop from enemies
Fragment of the Philosopher's Stone
Philosophers Stone Icon.png
You're officially the richest creature on the island. This absolutely perfect little jewel is worth 75000 GOLD! 75000
  • Random drop from enemies (0.2%)
  • Wall runes (incredibly rare)

Dead Man’s Bag[edit | edit source]

Dead Man's Bag.png

A bag that spawns at the start of Prisoners' Quarters. It contains some of the gold from your last run. The value depends on your current level of Gold Reserves and any gold above this limit is lost.

Cells centered[edit | edit source]

Cells are a special currency that is used primarily for unlocking items and upgrades. They're often dropped from slain enemies and bosses, or found in chests and canisters in biomes.

It is worth noting that all cells are lost on death.

Cells can be spent in two ways; unlocking items and upgrades from The Collector, or by increasing the chance for higher quality gear to appear in runs from The Blacksmith.

Liposuction[edit | edit source]


A rare pickup that produces one extra cell on every kill for 45 seconds, even if the enemy didn’t drop a normal cell. It randomly drops from enemies, but the exact chance is unknown.

Residual Cells[edit | edit source]

Residual Cells.png

A bag that spawns next to the Dead Man's Bag if you defeated The Hand of the King. It contains any cells possessed upon reaching the Throne Room, as well as the 40 cells dropped by the Hand of the King. If not picked up, or if the run is reset, the cells will be lost.

Other Pickups[edit | edit source]

Bonus Point Stars[edit | edit source]

See the main article for information about Bonus Point Stars.

Bonus Point Star.png

Bonus Point Stars are exclusively found in the Daily Run. They give a 5-point bonus for each enemy killed for 15 seconds.

Secret Potion of ???[edit | edit source]

Keys[edit | edit source]

Unlike most pickups, keys are not used when they are picked up. Instead, they are added to the player's inventory, so they can be used later to open their respective doors. Keys remain in the player's inventory for the rest of the run if not used on the appropriate door. Unused keys disappear upon death or at the end of a successful run.

Name Icon Location Description
Gardener's Key
Gardener's Key.png
Promenade of the Condemned 3 Gardener Keys are required to obtain the Explosive Crossbow blueprint.
  • The first key requires the Ram Rune
  • The second needs the Spider Rune or the Homunculus Rune
  • The third can be obtained by stomping a hidden flower in the ground three times.

After the Explosive Crossbow blueprint is collected, there will be Malachite or Amethyst in its place on subsequent runs as well as a random weapon or skill. The doors will also be permanently open.

In each of the Ramparts, the Graveyard, and the Forgotten Sepulcher, there is a secret room with a door unlocked by a Gardener Key, behind which is a Moonflower Key.

Iron Cells Key
Iron Cells Key.png
Prison Depths, Corrupted Prison Dropped by enemies inside the biome. Used to open 1 of 2 cell doors at the end of the biome, which grants the player a random item. Only 1 may spawn each run.
Old Service Key
Old Service Key.png
Ancient Sewers 3 Old Service Keys are dropped by enemies in the Ancient Sewers and are used to open any of the 8 doors at the end of the biome.

It stinks.

Village Key
Village Key.png
Stilt Village 2 Village Keys open doors further in the level. The mid-stage door can be bypassed with the Spider Rune, but the doors blocking the Clock Tower and Forgotten Sepulcher cannot be bypassed. A secret area in the village requires this key to unlock access to its prize, the blueprint for the Parry Shield.
Clockmaker's Key
Clockmaker's Key.png
Clock Tower Opens the door blocking the exit to the Clock Room.
Bell Tower Key
Bell Tower Key.png
Clock Tower Drops from a Clock Tower bell when all 4 are rung in ascending order of the pitch of their ring[1]. Opens the door blocking the blueprint for Punishment.
Graveyard Key
Graveyard Key.png
Graveyard Opens the door leading into the underground portion of the graveyard.

Open the gates of Hell...

Architect's Key
Architect's Key.png
Graveyard (inside a wall rune) Opens the door blocking the blueprints for Merchandise Categories and Parting Gift.
Crypt Key
Crypt Key.png
Forgotten Sepulcher 2 Crypt Keys are found throughout the biome, each letting player progress further in the level. They are all behind Teleportation Tombs.

2 Additional keys can be found if the player does not have the Explorer's rune, which are dropped by 2 Elite Dark Trackers and used to unlock the doors leading to the rune. Once the rune is collected these keys won't appear again.

It seems to be very old.

Moonflower Key
Moonflower Key.png
Ramparts, Graveyard, Forgotten Sepulcher There are 3 Moonflower Keys:

Each appears in a secret room reached with a well-hidden passage through the walls. A glimpse of the room may hint at the passage's location, which is faintly marked by vines. Inside each room is a door requiring a Gardener's Key from the Promenade of the Condemned to pick up to the Moonflower Key. Reaching all four of these locations in a single run requires having 3 active BSC and passing through the 3-cell door leading from the Ramparts to the Insufferable Crypt. If all Moonflower Keys are collected, they can access a secret room in High Peak Castle hidden in a similar way as the rooms containing the keys. The room contains the blueprint for Acceptance.

Castle Key
Castle Key.png
High Peak Castle There are 3 Castle Keys in High Peak Castle. They drop from the Elite enemies inside the colored doors. Only 2 are needed to proceed to the Throne Room, but the last grants access to a room where the player can find a Scroll of Power, 2 weapons, and the blueprint for the Boomerang.
Cavern Key
Cavern Key.png
Prisoners' Quarters (inside the break in the wall at the entrance of the level) Opens the door to the Cavern in the Graveyard.

Once unlocked, the door remains open for future runs. Otherwise, the key will continue to respawn.

Garland Key
Garland Key.png
Cavern (in a ceiling secret space) Gives access to a gate in one 4 BSC door, which contains the blueprint of Festive Outfit.
Allen Key
Allen Key.png
Astrolab Dropped by an Elite Slammer. Used to open the door to the final section of the biome.
Elevator Key
Elevator Key.png
Astrolab Dropped by an Elite Failed Experiment. Opens the door to the elevator at the end of the biome.
Guardian's Key
Guardian's Key.png
Astrolab There are two Guardian's Keys. They are dropped by two Elite Slammers at the end of the final section of the biome.
Apex Key
Apex Key.png
Astrolab Found in a secret area, at the end of an obstacle course. Used to open the door to the button that lets the blueprint for Sonic Carbine drop.
Dilapidated Arboretum Key
Dilapidated Arboretum Key.png
Prisoners' Quarters (near entrance to Dilapidated Arboretum from the deceased Royal Gardener) Opens the door to the Dilapidated Arboretum. Once unlocked, the door despawns from future runs, unless the player doesn't have the DLC.
Distillery Key
Distillery Key.png
Derelict Distillery behind a wall that needs to be broken with an explosive barrel. Opens the door to the exit of the biome.

A colorless Barrel Launcher can be found next to the wall it is behind.

Removed Pickups[edit | edit source]

Removed gems[edit | edit source]

Name Icon Description Value Sources
Golden Cell
Golden Cell Icon.png
A little gold cell worth 20 GOLD. 20 One per Cell while an amulet with the "Get gold as well as a cell" affix was worn.

With v1.9, the Update of Plenty, this affix was removed due to the economy rework, thus effectively removing this gem as well.

Removed keys[edit | edit source]

Name Icon Location Description
Fool Key
Fool Key.png
Ossuary, Ancient Sewers Dropped from a Zombie elite and an Inquisitor elite that spawned from a Christmas present that also gave the player a 5 enemies curse.

This key was later removed from the game and was only replaced in the Ancient Sewers with the Old Service Key.

Gold Cells Key
Gold Cells Key.png
Prison Depths Dropped by enemies inside the biome. Used to open a cell door at the end of the biome, which grant the player one Scroll.

With v1.5, the Corrupted Update, they were removed in place of a Cursed Chest at the beginning of this biome, which gives one Scroll of Power.

References[edit | edit source]

Navigation wiki

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